Speedy brain stimulation for persistent negative symptoms in schizophrenia
Part of Mental health clinical trials.
This trial tests if a new, faster form of brain stimulation called accelerated neuromodulation therapy can help reduce negative symptoms (like loss of motivation or social withdrawal) in people with schizophrenia. It aims to see if this treatment can improve daily functioning and quality of life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a diagnosis of schizophrenia, schizoaffective disorder, or a related condition for at least 6 months.
- You must have significant negative symptoms (like having trouble with motivation or social activities).
- Your current medication must have been the same for at least 4 weeks before starting.
- Your symptoms must have been stable for at least 3 months (no major changes).
- You must be able to have an MRI scan and have no medical reasons that prevent brain stimulation.
- You cannot have had electroconvulsive therapy (ECT) in the past 6 months, or previous treatment with repetitive TMS.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a faster type of brain stimulation, called accelerated neuromodulation therapy, in people who have early signs that could lead to psychosis. The goal is to see if this treatment can help reduce symptoms and improve daily life.
This trial tests whether a non-invasive brain stimulation technique called nTMS (repetitive transcranial magnetic stimulation) can help reduce negative symptoms of schizophrenia, like lack of motivation or social withdrawal. It's a possible treatment option for people with stable schizophrenia who still struggle with these symptoms.
This trial tests a faster form of brain stimulation called accelerated intermittent theta burst stimulation to help with persistent negative symptoms of schizophrenia. Negative symptoms include things like lack of motivation, reduced emotion, or social withdrawal.
This trial uses repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation technique, to treat persistent negative symptoms (like lack of motivation or social withdrawal) in people with schizophrenia. You'll be in a stable phase and your negative symptoms must have lasted at least 6 months.
This trial tests a newer form of brain stimulation called multi-target TMS (transcranial magnetic stimulation) to help reduce negative symptoms of schizophrenia—like reduced emotion, motivation, and speech—in people whose symptoms aren't fully controlled by medication alone.
This trial tests combining two types of non-invasive brain stimulation (HD-tDCS and iTBS) to help with negative symptoms of schizophrenia, such as lack of motivation or social withdrawal. The goal is to see if this combination can improve these symptoms that are often hard to treat with medication alone.
Hear when a new Schizophrenia and Predominant Negative Symptoms trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.