Personalised brain stimulation for persistent negative symptoms
Part of Brain & nervous system, Mental health clinical trials.
This study tests a type of brain stimulation (repetitive transcranial magnetic stimulation, or rTMS) to see if personalising it based on individual brain profiles can improve persistent negative symptoms (such as lack of motivation or social withdrawal) in schizophrenia. It may help determine which patients are most likely to benefit from this treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 70 years old
- You are fluent in French (at least B2 level)
- You have a diagnosis of schizophrenia or a related disorder, and have had at least 2 negative symptoms (like apathy or lack of emotion) for at least 6 months
- You are willing to undergo MRI scans and brain stimulation sessions
- You have been on a stable medication regimen for at least 6 weeks
- You are not currently taking certain antiseizure drugs (unless it is lamotrigine or long-term benzodiazepines)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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