Pain relief after knee replacement: Zynrelef vs standard injections
Treatments studied
Part of Bones, joints & muscles clinical trials.
This study compares two types of pain relief for people having knee replacement surgery: a newer long-acting medication called Zynrelef versus the usual injections given around the knee. The goal is to find out which works better for controlling pain after surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 89 years old
- You have knee osteoarthritis and are scheduled for a total knee replacement on one knee
- You are not pregnant, a child, or currently in prison
- Your body mass index (BMI) is no more than 45
- You have not taken strong painkillers (like opioids) daily for more than a month before the study
- You have no known severe allergies to NSAIDs or numbing medications
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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