Pain relief after knee replacement: Zynrelef vs. standard injections
Treatments studied
Part of Bones, joints & muscles clinical trials.
This study compares two ways of managing pain after a partial knee replacement. It tests a new pain medication placed in the knee during surgery against the usual numbing injection, to see which provides better relief and recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 89 years old
- You have knee osteoarthritis and are scheduled for a partial knee replacement (unicompartmental knee replacement)
- Your body mass index (BMI) is 45 or less
- You have not taken strong opioid painkillers regularly for more than a month
- You are not allergic to non-steroidal anti-inflammatory drugs (like ibuprofen) or numbing medicines
- You do not have severe kidney disease
- You have not had a knee replacement on the other side within the past 2 years
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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