Apixaban vs warfarin after heart valve repair or tissue valve replacement
Part of Heart & circulation clinical trials.
This study compares two blood-thinning medicines, apixaban and warfarin, for people who had heart valve repair or a tissue (biological) valve replacement and also have atrial fibrillation. It aims to see which medicine is safer and works better in the first three months after surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You had heart valve repair or a tissue (biological) valve replacement within the last 10 days.
- You have atrial fibrillation (irregular heartbeat) that requires blood thinners.
- You do not have a mechanical (metal) valve.
- You have no severe kidney or liver problems, active bleeding, or conditions that increase bleeding risk.
- You are not pregnant or planning to become pregnant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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