Blood thinner pill vs warfarin after mechanical aortic valve
Treatments studied
Part of Heart & circulation clinical trials.
This study compares a blood thinner pill (a factor Xa inhibitor) with warfarin (vitamin K antagonist) in people who have had a mechanical aortic valve replacement. It looks at which option works better and is safer over the long term.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 19 years old or older
- You had a mechanical aortic valve replacement at least 3 months ago
- Your valve is working well and fits the study’s heart/valve criteria, or you have mild symptoms (NYHA class I or II)
- You agree to take part in the study by signing the written consent form
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two blood-thinning medicines, edoxaban and apixaban, to see which one is better at preventing strokes and bleeding in people who have both atrial fibrillation and coronary artery disease. If you're eligible, you may receive one of these standard treatments, and the trial could help find the safer option.
This trial compares two blood-thinning treatments after aortic valve replacement with a tissue valve. It tests if a convenient pill (apixaban) is as safe and effective as aspirin alone, to prevent blood clots and other complications. Participation could help improve recovery and reduce the risk of strokes and bleeding.
This trial compares two medicines to prevent blood clots after heart valve surgery. If you've had a tissue valve replaced or repaired, this study will see if a newer blood thinner (rivaroxaban) is safer and works better than the standard treatment.
This trial compares a newer blood thinner (rivaroxaban) to the standard one (warfarin) for people with mechanical heart valves who have had clots or bleeding while on warfarin, or who cannot easily monitor their INR levels. It aims to see if rivaroxaban is safer and more effective.
This study compares two blood-thinning medicines, apixaban and warfarin, for people who had heart valve repair or a tissue (biological) valve replacement and also have atrial fibrillation. It aims to see which medicine is safer and works better in the first three months after surgery.
This trial compares two ways to prevent blood clots after open heart surgery: a “direct oral” blood thinner pill versus warfarin (a vitamin K antagonist). It may help find the safest and most effective option for people who develop atrial fibrillation after surgery.
Hear when a new Thromboembolism trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.