Bone-strengthening drug plus antibiotic for chronic bone infection
Treatments studied
Part of Bones, joints & muscles, Infections clinical trials.
This study tests whether adding a bone-strengthening drug (bisphosphonate) to standard antibiotics (vancomycin) helps clear chronic bone infections (osteomyelitis) caused by Staph or MRSA, after surgery. It may help improve healing and prevent the infection from coming back.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a long-term bone infection (osteomyelitis) that needs surgery to clean out infected bone.
- Testing shows the infection is caused by Staphylococcus aureus bacteria, including the harder-to-treat MRSA type.
- You are between 18 and 65 years old.
- You are not pregnant or breastfeeding.
- Your kidneys are working well (no serious kidney disease).
- You have not used bisphosphonate medications (for bone thinning) recently, and your blood calcium is normal.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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