Platelet gel for healing after tooth removal
Part of Bones, joints & muscles, Mouth & dental clinical trials.
This study tests whether using a concentrate of your own platelets (cells that help blood clot and heal) in the tooth socket after removal improves healing and reduces the risk of a jaw bone condition called MRONJ. It may be an option if you are at higher risk for MRONJ due to certain medications.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 25 years or older.
- You need to have one or more back teeth (premolars or molars) removed that cannot be saved.
- You are at higher risk for MRONJ because you take or have taken certain bone-strengthening or cancer medications, such as bisphosphonates or denosumab, or you have had MRONJ before.
- You are not pregnant or breastfeeding.
- You have not had radiation therapy to the jaw area and do not have cancer that has spread to the jaw.
- You are not a current smoker and have not smoked (including e-cigarettes) for at least 10 years.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether a special gel made of polynucleotides and hyaluronic acid (molecules that help tissue repair) can improve healing after jaw surgery for early-stage medication-related osteonecrosis. The gel is applied during surgery to support the bone and gum healing.
This study tests whether a special blood clot placed in the tooth socket after a dental extraction can help prevent a jaw bone problem called osteoradionecrosis, which can happen in people who had radiation for head and neck cancer. If you need a tooth pulled in an area that was previously radiated, this treatment might reduce the risk of bone damage and help you heal better.
This study tests a special blood-derived gel called leukocyte and platelet-rich fibrin (L-PRF) to help prevent jawbone damage after tooth extraction in people who have had head or neck radiation or take bone-strengthening medications. L-PRF is made from a small amount of your blood and placed in the extraction socket to promote healing.
This trial tests whether a special dressing made from your own blood (called L-PRF) can help your jaw heal better after surgery for medication-related bone damage. It's for people who need surgery for this condition and aims to improve recovery.
This study tests if a gel made from your own blood can help your gums heal faster after a back tooth is removed. It is for patients getting dental care at the University of Nebraska Medical Center.
This study looks at how age affects healing after a tooth is removed and replaced with a bone graft using Platelet-Rich Fibrin (PRF), a natural substance from your own blood that helps healing. It may help you if you need a molar removed and plan to get an implant later.
Hear when a new Medication Related Osteonecrosis of the Jaw trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.