Catheter ablation for advanced atrial fibrillation
Part of Heart & circulation clinical trials.
This trial tests a special type of catheter ablation (using electric pulses called electroporation) to treat people with long-lasting atrial fibrillation and a very enlarged left atrium. It may offer a new treatment option when standard approaches are limited.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have persistent or long-standing persistent atrial fibrillation (a heart rhythm problem that lasts a long time).
- Your left atrium (one of the heart's upper chambers) is severely enlarged (measured by an imaging test as LAVI > 50 ml/m2).
- You are age 80 or younger.
- You have not had any previous ablation (a procedure that scars heart tissue to stop abnormal signals) in your left atrium.
- You do not have a blood clot in your left atrium, severe valve disease needing surgery, or a life-threatening condition.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a catheter ablation procedure for people with persistent atrial fibrillation (a type of irregular heartbeat that lasts more than 7 days but less than a year). It aims to see if the procedure is safe and effective for restoring a normal heart rhythm.
This trial tests a new type of ablation (pulsed-field) to treat persistent atrial fibrillation (AFib) that lasts more than 7 days. You may qualify if you have symptoms and haven't had other heart ablation procedures except for one specific type.
This trial tests a two-step procedure for persistent atrial fibrillation that combines a heart ablation with isolation of a small heart pouch. It aims to see if this approach is more effective than standard care.
This trial tests whether using a special heart-mapping device during ablation (a procedure to fix irregular heartbeats) can improve outcomes for people with persistent atrial fibrillation and an enlarged left heart chamber.
This trial is testing a specific approach to catheter ablation for people with persistent atrial fibrillation. It aims to improve how abnormal heart tissue is targeted to help restore a normal rhythm.
This trial tests a new type of catheter ablation (using heat to create scar lines in the heart) for people with persistent atrial fibrillation who have a higher risk of stroke or bleeding. It aims to see if this approach can help prevent strokes and reduce the need for long-term blood thinners.
Hear when a new Persistent Atrial Fibrillation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.