A new drug for high cholesterol from family genes
Treatments studied
Part of Genetic & congenital, Heart & circulation, Hormones & metabolism clinical trials.
This trial tests an experimental medication called QLC7401 for people with a genetic condition that causes very high cholesterol. It aims to lower cholesterol levels safely and may be an option for those who need better control.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- You have been diagnosed with heterozygous familial hypercholesterolemia (a genetic form of high cholesterol).
- Your LDL (bad) cholesterol is at least 2.6 mmol/L when tested.
- Your fasting triglycerides (another type of fat in blood) are below 4.5 mmol/L.
- If you take cholesterol medicines, you must have been on a steady dose for at least 4 weeks before starting the trial.
- Your kidney function (eGFR) is over 30, meaning kidneys are working well enough.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new injection called SYH2053 for people with HeFH, a genetic condition that causes very high cholesterol. It looks at whether the injection can safely lower LDL cholesterol when added to standard statin therapy.
This trial tests if a new drug, QLC7401, can lower cholesterol in people with high cholesterol who are not on other cholesterol medicines. It may be an option if you have low or medium risk of heart disease and no history of heart problems.
This trial tests a new medication (QLC7401) for people with high cholesterol that is not well controlled by their current treatment. It aims to see if the drug can help lower LDL-C (bad cholesterol) levels and reduce the risk of heart problems.
This trial tests an experimental drug, QLC7401, for people with high LDL cholesterol that hasn't lowered enough with current treatments. It aims to see if the drug can help reduce cholesterol levels in patients who are already on stable cholesterol medication.
This trial tests a new injection called ART002g1 for people with a genetic condition that causes very high cholesterol. It aims to see if the drug is safe and can help lower cholesterol levels.
This trial tests if a new medicine, lerodalcibep, can safely lower cholesterol in children ages 6 to 17 who have a genetic condition called heterozygous familial hypercholesterolemia (HeFH). It aims to help children whose cholesterol stays high despite taking standard cholesterol-lowering drugs.
Hear when a new Heterozygous Familial Hypercholesterolemia (HeFH) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.