Clin2
NCT07450430Likely a fitNot yet recruiting

Finding the best time to give ketamine for sickle cell pain

Sickle Cell DiseaseSickle Cell Crisis

Treatments studied

Part of Blood & lymphatic, Genetic & congenital, Pain clinical trials.

This trial looks at the best time to start giving ketamine, a pain-relieving medicine, for sickle cell pain. It aims to find out whether giving it earlier or later in your visit works better and is safer.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
90 people
Ages
6 years to 24 years
Study type
Interventional

Who can take part

  • You have sickle cell disease.
  • You are coming to the emergency room or infusion clinic because of pain.
  • You are between 6 and 24 years old.
  • You are not allergic to ketamine and have not had severe side effects from it in the past.
  • You (or your parent/guardian) can agree to participate.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07369024Recruiting· Phase 2
Study of low-dose ketamine for sickle cell pain crisis

This study tests whether a low-dose of ketamine (a pain medicine) can help children and young adults with sickle cell disease who are in a pain crisis. It aims to provide better pain relief while avoiding some side effects of standard painkillers.

Torrance, California
NCT07826988Not yet recruiting· Phase 4
Comparing pain medicines for sickle cell crisis in hospital

This trial compares different ways to manage sickle cell pain crises in the hospital, using a flexible 'platform' design to test combinations of pain medicines. It aims to find the safest and most effective approach to reduce pain and improve recovery.

NCT06989567Not yet recruiting· Phase 3
L-citrulline for sickle cell pain crises

This trial tests an intravenous medicine called L-citrulline for young people with sickle cell disease who are in the emergency department for a painful crisis (vaso-occlusive crisis). It aims to see if it can ease the pain and help you recover faster.

Washington D.C., District of Columbia
NCT06930703Recruiting· Phase 1/Phase 2
CBD for sickle cell pain

This trial tests if cannabidiol (CBD) can help reduce pain interference in adults with sickle cell disease. You will take CBD daily for 4 weeks and report your pain levels.

Manhattan, New York
NCT06725550Recruiting
Acupuncture for pain in sickle cell disease

This trial tests whether adding acupuncture to standard pain treatments can help manage pain in people with sickle cell disease. It involves brain scans, questionnaires, and acupuncture sessions to see if this approach reduces pain and improves quality of life.

Cincinnati, Ohio
NCT06635902Recruiting· Phase 2
Citrulline for sickle cell pain crisis

This trial tests if an intravenous medication called L-citrulline can help treat pain crises in children and young adults with sickle cell disease. Participants receive either the study drug or a placebo while in the hospital for a severe pain episode.

Washington D.C., District of Columbia

Hear when a new Sickle Cell Disease trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.