Clin2
NCT07453888Possibly a fitRecruiting

Nose spray for sudden vision loss from optic nerve damage

Non-Arteritic Anterior Ischemic Optic Neuropathy

Part of Brain & nervous system, Eyes & vision, Heart & circulation clinical trials.

This trial tests a nose spray medication (cenegermin) for people who recently lost vision due to a specific type of optic nerve damage (NAION). The goal is to see if it can help restore sight when started within two weeks of vision loss.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
272 people
Ages
50 years to 80 years
Study type
Interventional

Who can take part

  • You must have sudden vision loss in one eye caused by a problem with the optic nerve (NAION), diagnosed by a doctor.
  • Your vision loss must have started less than 14 days ago.
  • Your vision in the affected eye should be between roughly 20/30 and 20/1000 on an eye chart.
  • You cannot have vision loss in both eyes from this condition, or a history of giant cell arteritis.
  • You must not have glaucoma or high eye pressure in the affected eye, or certain types of age-related macular degeneration.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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