Orbital blood vessel inflammation in optic nerve disease
Part of Brain & nervous system, Eyes & vision, Heart & circulation, Immune system & allergy, Skin clinical trials.
This study uses MRI scans to look at inflammation in blood vessels around the eye in two conditions: giant cell arteritis (GCA, a type of blood vessel inflammation) and ischemic optic neuropathy (a condition where the optic nerve doesn't get enough blood). The goal is to better understand how inflammation affects the optic nerve and vision, which could help guide future treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 50 years or older.
- You have been newly diagnosed with either ischemic optic neuropathy or giant cell arteritis (GCA).
- If you have GCA, you must not have any vision changes (like vision loss or double vision) from the GCA.
- If you have ischemic optic neuropathy, you must have symptoms like a swollen optic nerve, vision loss, or a specific pupil defect.
- You have not been treated with prednisolone (a steroid) for more than 5 days before joining.
- You do not have any metal implants (like pacemakers or aneurysm clips) that would make an MRI unsafe.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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