Clin2
NCT07455149Possibly a fitNot yet recruiting

Intestinal bacteria and fatty liver disease study

Metabolic Dysfunction-associated Fatty Liver Disease

Part of Digestive system, Hormones & metabolism clinical trials.

This study looks at how a specific gut bacteria (Ruminococcus gnavus) and the chemicals it makes are linked to a type of fatty liver disease called MAFLD. By joining, you'll help researchers understand this connection, which may lead to better treatments in the future.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
200 people
Ages
18 years and older
Study type
Observational

Who can take part

  • You are an adult (over 18 years old).
  • You are either a healthy person with no liver disease, or you have been diagnosed with MAFLD (fatty liver disease linked to metabolism).
  • If you have MAFLD, your diagnosis must be confirmed by imaging (like an ultrasound) or a liver biopsy showing fat in more than 5% of liver cells, and you must have at least one sign of metabolic syndrome (like high blood pressure, high blood sugar, or abnormal cholesterol).
  • You have no other serious liver, stomach, kidney, or autoimmune diseases, and no history of cancer.
  • You have not had an acute infection or inflammatory illness in the past month.
  • You have not used laxatives, antibiotics, probiotics, prebiotics, proton pump inhibitors (like omeprazole), or other gut-affecting medications in the past month.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06939569Recruiting
Studying fatty liver disease in people with inflammatory bowel disease

This study looks at how common non-alcoholic fatty liver disease is in people with inflammatory bowel disease (Crohn's or colitis). Researchers want to learn more about the link between the two conditions.

Shanghai
NCT06739330Recruiting
Thyroid function and fatty liver disease study

This study looks at how your thyroid might be linked to fatty liver disease (MAFLD). It aims to help researchers understand if thyroid problems play a role in this condition, which could lead to better treatments.

Tanta, El-Gharbia
NCT07455175Not yet recruiting
Gut bacteria and liver cirrhosis study

This study looks at how gut bacteria change in people with liver cirrhosis and whether these changes relate to how the disease progresses. It may help find new ways to monitor or treat cirrhosis.

Guangzhou, Guangdong
NCT06585982Recruiting
Synbiotics for MAFLD: gut health and liver fat study

This trial tests whether taking a synbiotic (a mix of helpful bacteria and fiber) can improve insulin levels and reduce inflammation in people with Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD). It may help by changing the balance of bacteria in your gut.

Semarang, Semarang
NCT06873165Recruiting
Gut bacteria treatment for fatty liver disease

This study tests whether a specially designed gut bacteria treatment can help people with fatty liver disease and related health issues like high blood sugar, high cholesterol, or high blood pressure. It aims to see if the treatment is safe and improves liver health.

Taipei
NCT04141592Recruiting
Study immune and disease changes in fatty liver

This study looks at what drives non-alcoholic fatty liver disease and how it affects the body, including immune-related changes. You may be invited if you have confirmed fatty liver disease or, alternatively, if you are a healthy person with no liver disease.

London, Greater London

Hear when a new Metabolic Dysfunction-associated Fatty Liver Disease trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.