Clin2
NCT07465653Possibly a fitRecruiting

Study of HJB647 for heart failure with reduced pumping ability

Heart Failure With Reduced Ejection Fraction

Part of Heart & circulation clinical trials.

This trial tests a new medicine, HJB647, in people with heart failure who have a weak heart pump. It aims to see if the drug is safe and well-tolerated. You may qualify if your heart's pumping ability is reduced and you are on a specific standard therapy.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
12 people
Ages
18 years to 100 years
Study type
Interventional

Who can take part

  • You are 18 years or older
  • You have mild to moderate heart failure symptoms (NYHA class II or III)
  • Your heart's ejection fraction is less than 50%
  • Your NT-proBNP level is high (>=600 if normal rhythm, >=900 if atrial fibrillation)
  • You have been taking sacubitril/valsartan (at least 49/51 mg twice daily) for at least 4 weeks

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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