Apixaban vs warfarin for heart pump patients
Part of Brain & nervous system, Heart & circulation clinical trials.
This study compares two blood thinners for people who have a HeartMate 3 left ventricular assist device (LVAD). The goal is to see if the newer medicine, apixaban, works better or has fewer side effects than the standard medicine, warfarin.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a HeartMate 3 heart pump and have had it for at least 3 months.
- You must be 18 years old or older.
- You must currently be taking the blood thinner warfarin (brand name: Coumadin).
- If you are a woman who could become pregnant, you must not be pregnant and must use birth control.
- You must not have severe kidney problems, a known allergy to apixaban, a history of major bleeding on warfarin, or meet certain dose-reduction criteria.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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