Ear injection to help with hearing speech in noise for people with type 2 diabetes
Part of Brain & nervous system, Ear, nose & throat, Hormones & metabolism clinical trials.
This trial tests a new drug called Paliroden, given as an ear injection, to see if it is safe and can help people with type 2 diabetes who have trouble hearing conversations in noisy places. It is designed for those with normal to mild hearing loss but who still struggle with speech in noise.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 45 and 75 years old.
- You have had type 2 diabetes for at least 5 years, with recent blood sugar levels showing an A1c between 7% and 9%.
- You have normal hearing or only mild high-frequency hearing loss, but you have trouble understanding speech in noisy settings.
- You do not use hearing aids or cochlear implants.
- You have no history of ear infections, ear surgery (except ear tube placement over a year ago), or other ear problems.
- You are not pregnant, breastfeeding, or planning to become pregnant, and if you can become pregnant, you agree to use effective birth control during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a steroid injection directly into the inner ear to treat sudden, severe hearing loss that hasn't improved after 14 days of standard treatment. It may help people who have not responded to usual care.
This study tests how well people with cochlear implants can understand speech in noisy situations, compared to those with normal hearing. It involves a special imaging scan to see how the brain processes sound, which may help improve future implant technology.
This trial tests an oral medication, SPI-1005, given to adults receiving a cochlear implant to see if it improves hearing outcomes. It may help people with moderate to profound hearing loss who are scheduled for implant surgery.
This study tests if a cochlear implant fitting based on your ear's anatomy helps you hear speech in noisy places and enjoy music more. It is for people who are deaf in one ear and use a MED-EL cochlear implant.
This trial tests new sound-processing software in cochlear implants to help users hear speech better in noisy places. It may help adult implant users who struggle with conversations in background noise.
This trial tests a new way to deliver steroid medication directly into the inner ear through the eardrum to treat sudden hearing loss in one ear. The goal is to help restore hearing after standard treatments haven't fully worked.
Hear when a new Cochlear Synaptopathy trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.