Clinical trials
Coronary Atherosclerosis clinical trials
Below are recruiting coronary atherosclerosis clinical trials, each written for real people, not researchers. We’re tracking 60 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07521007RecruitingPhase 2
YN001 treatment for coronary artery disease
This study tests whether a new drug called YN001 can help people with coronary atherosclerosis (narrowing of heart blood vessels). The trial aims to see if it can improve outcomes in people who have early-stage blockages in their heart arteries.
Huntsville, AlabamaAges 18–80 - NCT05660798Recruiting
Switching from cigarettes to heat-not-burn to protect heart arteries
This study looks at whether switching from regular cigarettes to a tobacco heating product slows buildup of plaque in the heart arteries. You’d be guided through smoking change and monitored using heart scans, to see if artery plaque stays the same or improves.
WarsawAges 18–75 - NCT05994014Recruiting
Comparing two heart scans for artery blockages
This study compares two types of heart scans to see which one better finds blockages in the arteries of people with chest discomfort or shortness of breath when active. You will have both a special CT scan and a PET/CT scan to check the health of your heart arteries.
Baltimore, MarylandAges 18 years+ - NCT06253962Recruiting
Can carotid artery scans predict heart disease?
This study looks at whether ultrasound scans of the carotid artery (the main artery in your neck) can help predict blockages in the heart arteries. If you are getting both a carotid ultrasound and a heart angiogram, you may be able to join.
ShanghaiAges 14–90 - NCT06393894Recruiting
Latvian Early Atherosclerosis Registry Study
This study is gathering information from people with early heart artery blockages (occurring before age 55 for men or 65 for women) who need or have had treatment like stents or bypass. It helps doctors understand long-term outcomes.
RigaAges 18–65 - NCT03504956Recruiting
MRI study to map early heart artery plaque changes
This study uses an MRI scan to better “see and measure” early changes in the heart’s artery lining. It may help researchers understand coronary artery disease earlier, even before it causes symptoms.
Los Angeles, CaliforniaAges 18 years+ - NCT04674449Recruiting
Tests a targeted plan for people with chest pain from heart artery disease
This study aims to match people with angina (chest pain from heart artery problems) to the most helpful treatment plan based on their test results. It’s done around the time doctors are planning an invasive heart scan to look at the coronary arteries.
CorkAges 18 years+ - NCT06083155Enrolling by invitation
Dutch registry of coronary function tests
This study collects information from people who are already scheduled for a coronary function test, to learn more about heart vessel health. By joining, you help researchers understand patterns and improve care for others.
Nijmegen, GelderlandAges Any age - NCT05796739Recruiting
Stress testing once or only when needed for high calcium risk
This study compares two approaches to stress testing in people who feel fine but have high coronary artery calcium on a scan. It may help determine whether testing routinely is better than doing it only if symptoms or concerns arise.
SeoulAges 19 years+ - NCT06831409Recruiting
Heart scan study for retired NFL players
This trial uses heart CT scans to measure plaque and blood flow in retired NFL players, helping understand heart risks.
Greenwood Village, ColoradoAges Any age - NCT04827498Recruiting
Testing heart blood-flow problems without clogged arteries
This study looks at how well the heart’s blood vessels work in people who have symptoms of reduced blood flow but no major artery blockage. It uses special heart tests with medicines to check how the vessels respond and may help guide better diagnosis and treatment.
MadridAges 18 years+ - NCT07074847Enrolling by invitation
Heart artery microcirculation and metabolism study
This trial looks at the tiny blood vessels in the heart and how they work in people who have no major blockages. It may help understand chest pain that isn't caused by large artery narrowing.
Xi'an, ShaanxiAges 18–80 - NCT06700720RecruitingPhase 2
YN001-004 for coronary artery disease
This trial tests a new medicine (YN001) in people with coronary atherosclerosis (plaque buildup in heart arteries). It aims to see if the drug can help improve artery narrowing and heart health.
Canberra, Australian Capital TerritoryAges 18–75 - NCT03788512Recruiting
Registry study for recent stroke/TIA with heart artery disease
This study enrolls people who recently had an ischemic stroke or a TIA (a “mini-stroke”) and also have evidence of narrowed heart arteries. It collects information to better understand how brain and heart artery disease occur together and may guide future care.
Beijing, BJAges 18–85 - NCT06767345RecruitingPhase 4
Comparing two cholesterol medicines for plaque stabilization
This study compares two ways to lower cholesterol and stabilize artery plaque in people with coronary artery disease who are having a stent procedure. It tests whether a moderate statin plus ezetimibe works as well as a high-intensity statin alone for stabilizing plaque.
Seoul, SeoulAges 18 years+ - NCT06040073Recruiting
Study of heart artery blockages after heart attack
This study is for people who recently had a heart attack and need an angiogram. It looks at blockages that are not completely blocking blood flow to learn how they change over time.
BeijingAges 18 years+ - NCT07316452Recruiting
Early heart disease risk study for adults under 45
This study looks at what makes heart disease progress in younger adults (18 to 45). If you have symptoms of heart disease and have had a heart CT scan, joining this research might help doctors better predict and manage your condition.
BeijingAges 18–45 - NCT07276282RecruitingPhase 3
Ziltivekimab for heart attack patients with artery plaque
This trial tests a new drug called Ziltivekimab to see if it can reduce plaque buildup in the heart arteries after a heart attack. It may help prevent future heart problems by targeting inflammation.
BernAges 18 years+ - NCT06939374Recruiting
Freezing heart arteries to stabilize high-risk plaques
This study tests a special cooling balloon to freeze and stabilize dangerous plaques in heart arteries that are not the main cause of your current symptoms. It aims to prevent future heart attacks.
AalstAges 18 years+ - NCT03427996Recruiting
Study of rotational stent treatment in everyday care
This trial looks at how safe and effective rotational atherectomy (a procedure used to treat blocked heart arteries) is when used in routine clinical practice. It mainly gathers follow-up information from adults who already had this procedure.
Bucheon-siAges 19 years+ - NCT06519292Recruiting
Heart side effects from immunotherapy in cancer patients
This trial looks at whether immunotherapy drugs (checkpoint inhibitors) cause heart problems in people with certain cancers. It will help doctors understand who is at risk and how to monitor for side effects.
Amsterdam, North HollandAges 50 years+ - NCT07614230RecruitingPhase 4
SGLT2 drugs and heart artery health in diabetes
This study tests whether a diabetes medication called SGLT2 inhibitors can slow the buildup of plaque in heart arteries. Researchers will use special CT scans to track changes in your coronary arteries over time.
Beijing, Beijing MunicipalityAges 18–78 - NCT07091682Recruiting
A trial of a dissolvable heart stent for long blockages
This trial tests a new type of stent made from magnesium that slowly dissolves over time. It is for people who have a long blockage in a heart artery that has not been treated before and may be a good option for those who are stable and have not had a recent heart attack.
ErfurtAges 18–80 - NCT06588244Recruiting
Registry for chest pain with open arteries
This study is looking at people who have chest pain or shortness of breath but whose heart arteries look fairly open on an angiogram. It aims to understand why they have symptoms and how to improve care. You may qualify if you're having a coronary angiogram and it shows no major blockages.
Naples, ItalyAges Any age
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Common questions
- Are there clinical trials for coronary atherosclerosis?
- Yes. Clin2 currently lists 60 recruiting coronary atherosclerosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary atherosclerosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary atherosclerosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.