Treatment
Ezetimibe clinical trials
We’re tracking 30 recruiting studies that include Ezetimibe, each written for real people, not researchers, below.
Recruiting studies
- NCT07036991Recruiting
Comparing two treatments for narrowed neck arteries
This trial tests whether adding a PCSK9 inhibitor to a statin is better than a statin alone for people with mild-to-moderate narrowing of the carotid artery (the main artery in the neck). It looks at how well these treatments slow plaque buildup and prevent strokes.
ShanghaiAges 18 years+ - NCT06686615Recruiting
Study of a triple cholesterol medicine combination in high-risk patients
This study tests a cholesterol-lowering combination of three medicines: bempedoic acid, ezetimibe, and a statin (atorvastatin or rosuvastatin). It is for people with high cholesterol, especially those at high risk for heart problems, who need stronger treatment.
Braunau am InnAges 18 years+ - NCT05782777Recruiting
Cholesterol medicines after stent: combo pill vs single pill
This trial compares two cholesterol-lowering treatment plans after a heart procedure where new drug-eluting stents were placed: a combination of high-intensity statin plus ezetimibe versus high-intensity statin alone. It may help find which option lowers cholesterol more effectively and safely over the first year after the procedure.
SeoulAges 19 years+ - NCT06784557RecruitingPhase 4
Study of ezetimibe's effect on gut bacteria
This trial tests whether ezetimibe, a cholesterol-lowering drug, changes the bacteria in your gut. It may help people with heart disease or high cholesterol who are already on a statin.
SeoulAges 19–80 - NCT07206472Recruiting
Study of bempedoic acid for high cholesterol
This study observes patients with high cholesterol or mixed lipid disorders who are taking bempedoic acid, alone or with ezetimibe, to see how it works in real life. It aims to gather information that may help doctors better manage cholesterol.
Belo HorizonteAges 18 years+ - NCT04499859RecruitingPhase 4
Low-dose cholesterol medicines versus high-dose after heart attack
This study compares two cholesterol treatment approaches after a heart attack: a lower dose combination versus a higher dose single medicine. It aims to see which option works well and is tolerable for people after a treated heart attack.
Bucheon-si, GyeonggidoAges 19 years+ - NCT04701242Recruiting
Early cholesterol medicine after heart attack
This trial looks at when and how to use cholesterol-lowering treatment soon after a heart attack. It may help people lower LDL (“bad” cholesterol) safely in the first days after an acute event.
AswānAges 18–100 - NCT04968509RecruitingPhase 3
PCSK9 shots for calcified aortic valve narrowing
This study tests whether adding PCSK9 inhibitor injections (to statin treatment) can slow or improve calcific aortic valve stenosis, a condition where the heart’s aortic valve becomes stiff and narrowed. It’s aimed at adults with mild-to-moderate disease or certain people with severe disease but no symptoms.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05845424RecruitingPhase 4
High-intensity cholesterol pills for people with silent calcium
This trial studies whether high-intensity statin plus ezetimibe can improve heart health in people who do not have symptoms but have calcium buildup in their heart arteries. It may help lower cholesterol and reduce future heart risks for the right participants.
SeoulAges 40 years+ - NCT06186037RecruitingPhase 4
Lower-dose combo vs. higher-dose alone for heart artery disease
This trial compares a lower-dose cholesterol pill (rosuvastatin plus ezetimibe) to a higher-dose version of just rosuvastatin for people with mild to moderate heart artery blockages who have not had a stent or bypass. It aims to see which approach works better and is safer.
Suwon, Gyeonggi-doAges 19 years+ - NCT06722521RecruitingPhase 4
Comparing two treatments for high coronary calcium without symptoms
This trial compares a combo of statin and ezetimibe without aspirin against statin alone with aspirin in people with high coronary calcium but no blocked arteries. It aims to find which approach is safer and more effective without causing bleeding risk.
SeoulAges 19 years+ - NCT06767345RecruitingPhase 4
Comparing two cholesterol medicines for plaque stabilization
This study compares two ways to lower cholesterol and stabilize artery plaque in people with coronary artery disease who are having a stent procedure. It tests whether a moderate statin plus ezetimibe works as well as a high-intensity statin alone for stabilizing plaque.
Seoul, SeoulAges 18 years+ - NCT06789432RecruitingPhase 4
Combination vs single cholesterol drug for Bangladeshi patients
This study tests whether a combination of two cholesterol-lowering medicines (atorvastatin and ezetimibe) works better than a higher dose of one medicine alone in Bangladeshi adults with high cholesterol and low to moderate heart risk.
Dhaka, Dhaka DivisionAges 18 years+ - NCT07307989RecruitingPhase 2
Statin plus ezetimibe vs. statin alone after stroke
This trial compares two treatments for people who recently had a stroke or TIA and have high cholesterol with artery plaque. Some participants will get a combination of two cholesterol-lowering medicines (statin and ezetimibe), while others will get only a statin.
PoziAges 20–100 - NCT07359105Recruiting
Statin vs. LDL Goal Therapy for Older Adults with Diabetes
This trial compares two approaches to lower cholesterol in people aged 70+ with type 2 diabetes: a moderate statin dose versus adjusting treatment to reach a personalized LDL-C target. It aims to find which strategy better prevents heart problems.
SeoulAges 70 years+ - NCT07524101Recruiting
Statin and Ezetimibe for Heart Disease and Kidney Disease
This trial tests whether taking a moderate-strength statin (cholesterol-lowering drug) plus ezetimibe (another cholesterol medicine) together helps protect the heart and kidneys in people who have both chronic kidney disease and established heart disease or stroke history.
SeoulAges 19–85 - NCT05579626Enrolling by invitationPhase 4
Low-dose statin plus ezetimibe vs high-dose statin for prediabetes
This trial compares two cholesterol-lowering approaches in people with prediabetes to see which one is less likely to lead to new-onset diabetes. It may help you choose a safer medication plan if you need strong cholesterol treatment to prevent future heart problems.
Bucheon-siAges 18–75 - NCT07704918Recruiting
Study: Lowering cholesterol during melanoma immunotherapy
This study tests whether giving aggressive cholesterol-lowering medication to people starting immunotherapy for melanoma can improve heart health. It may help reduce the risk of heart problems during cancer treatment.
Aurora, ColoradoAges 55 years+ - NCT05103254Recruiting
Pregnancy monitoring for bempedoic acid medicine use
This study follows people during and after pregnancy who took bempedoic acid (either alone or with ezetimibe). It collects safety information to better understand how this medicine may affect pregnancy outcomes.
Morrisville, North CarolinaAges 18 years+ - NCT05365438RecruitingPhase 4
Atorvastatin plus omega-3 for artery plaque in type 2 diabetes
This trial studies whether a combination of atorvastatin and omega-3 can reduce signs of artery plaque in people with type 2 diabetes and “mixed” cholesterol problems. It’s focused on people who don’t have symptoms from plaque yet.
Seongnam-si, Gyeonggi-doAges 20–80 - NCT05641753RecruitingPhase 4
LDL-lowering study for adults with type 1 diabetes
This study looks at cholesterol lowering in adults with type 1 diabetes and whether it reduces “residual risk,” meaning risk that may remain even with current care. You may be asked to take cholesterol-focused treatment and complete blood tests to track LDL (“bad cholesterol”).
New York, New YorkAges 18–89 - NCT06231966Recruiting
High-dose statin combo vs. standard statin for artery disease
This trial compares a high-dose combination of rosuvastatin (a statin) and ezetimibe (another cholesterol-lowering drug) versus a standard rosuvastatin-only approach for people with peripheral artery disease (narrowed leg arteries) or widespread artery disease. The goal is to see which strategy better lowers LDL cholesterol and reduces heart and limb risks.
SeoulAges 19–80 - NCT06437574RecruitingPhase 2
Cholesterol-lowering and immune response in prostate cancer
This trial tests whether taking a daily cholesterol-lowering medication (Vytorin or ezetimibe) can boost your immune system to help fight prostate cancer. It is for men with low- or intermediate-risk prostate cancer who are on active surveillance and planning a biopsy.
Los Angeles, CaliforniaAges 18 years+ - NCT06567418Recruiting
Early use of PCSK9i in Chinese heart attack patients
This study looks back at medical records of Chinese patients who had a heart attack or unstable angina. It compares outcomes for those who started a newer cholesterol-lowering shot (Alirocumab, brand name Praluent) plus a statin while in the hospital, versus those who only took a statin pill. The goal is to see if starting the shot early helps improve heart health.
Beijing, Beijing MunicipalityAges 18 years+
What Ezetimibe is being studied for
Conditions with recruiting Ezetimibe studies.
Common questions
- Are there clinical trials studying Ezetimibe?
- Yes. Clin2 currently lists 30 recruiting studies that include Ezetimibe, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Ezetimibe trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Ezetimibe an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Ezetimibe or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.