Blood-based dosing of SSRIs for hospitalized depression
Treatments studied
Part of Mental health clinical trials.
This study tests whether adjusting the dose of common antidepressants (SSRIs) based on regular blood tests can help people in the hospital feel better faster. It is for adults and teens age 12 and older with moderate to severe depression who are starting fluoxetine, escitalopram, or sertraline.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 12 years old or older.
- You have moderate to severe depression, and your doctor plans to start treatment with fluoxetine (Prozac), escitalopram (Lexapro), or sertraline (Zoloft).
- You are not currently taking one of these SSRI medications for this episode of depression, or you've stopped taking it long enough for it to leave your body.
- You do not have other mental health conditions like schizophrenia, bipolar disorder, or an intellectual disability.
- You are not pregnant, breastfeeding, or planning to become pregnant, and you agree to use effective birth control if needed.
- You do not have a severe untreated physical illness (like liver or kidney failure) or take medications that could interfere with these drugs.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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