Clin2
NCT07485751Worth exploringNot yet recruiting

Nasal spray from stem cells for treatment-resistant schizophrenia

Schizophrenia Negative Type

Part of Brain & nervous system, Ear, nose & throat, Mental health clinical trials.

This study tests whether a nasal spray containing tiny particles from dental stem cells (called exosomes) is safe and can help with 'negative symptoms' of schizophrenia, such as lack of motivation or emotion. It's a very early-stage trial for people who haven't gotten enough relief from standard treatments.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
15 people
Ages
18 years to 60 years
Study type
Interventional

Who can take part

  • You have been diagnosed with schizophrenia.
  • You are between 18 and 60 years old.
  • You have been in the hospital for more than 5 years.
  • Your symptoms have been stable for the last 6 months, and you haven't changed medications in the last 2 months.
  • Your usual medications (including clozapine) haven't helped enough.
  • You have moderate to severe 'negative symptoms' (like lack of motivation or emotion).
  • You are not pregnant, breastfeeding, or planning to get pregnant during the study.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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