Tocilizumab for depression with inflammation
Treatments studied
Part of Brain & nervous system, Mental health clinical trials.
This trial tests a medication called tocilizumab, which targets inflammation, to see if it can improve symptoms of major depression in people with signs of inflammation. You may be eligible if you have depression with a high monocyte count and significant loss of interest or pleasure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 70 years old.
- You have a diagnosis of major depressive disorder (MDD) and are currently in a depressive episode.
- A blood test shows your monocyte count is 500 or higher (a sign of inflammation).
- You have lost interest or pleasure in things (score of 20 or more on a standard questionnaire).
- You have no history of schizophrenia, bipolar disorder, or psychosis.
- You are not at serious risk of suicide or self-harm.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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