Chemo + venetoclax + immunotherapy for adult ALL
Treatments studied
Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.
This trial combines a kid-inspired chemotherapy backbone with a targeted pill (venetoclax) and immunotherapy (special antibodies) to treat adults with Ph-negative acute lymphoblastic leukemia (ALL). The goal is to use a more effective, less toxic approach developed for children.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be newly diagnosed with a type of leukemia called Ph-negative ALL (no Philadelphia chromosome) and have had little or no treatment yet.
- You must be between 14 and 60 years old.
- Your liver, kidneys, and heart must be working well enough.
- You should be able to take care of yourself (ECOG score 0, 1, or 2).
- If you could become pregnant, you must agree to use effective birth control.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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