Chemotherapy plus CAR-T for newly diagnosed Ph- B-ALL
Treatments studied
Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.
This trial tests giving chemotherapy together with a special immune cell treatment called CAR-T cells for adults who have just been diagnosed with a specific type of leukemia (Ph- B-ALL). The goal is to see if this combination works better than standard treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a type of leukemia called Philadelphia chromosome-negative B-cell acute lymphoblastic leukemia (Ph- B-ALL) that is newly diagnosed.
- You must be 18 years old or older.
- Your leukemia cells must have a protein called CD19 on their surface.
- Your major organs (kidneys, liver, heart) must be working well enough for treatment.
- You should not have active leukemia in your brain or spinal cord, or serious infections.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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