Clin2
NCT07497893Possibly a fitNot yet recruiting

Fexuprazan with blood thinners for atrial fibrillation

Atrial Fibrillation (AF)Upper Gastrointestinal Bleeding (UGIB)Gastrointestinal Hemorrhage (Clinically Important, Upper)Drug-Related Side Effects and Adverse Reactions

Treatments studied

Part of Digestive system, Heart & circulation clinical trials.

This study tests whether adding fexuprazan, a stomach-protecting medicine, to standard blood thinners reduces stomach bleeding in people with atrial fibrillation who are at higher risk for bleeding. It aims to see if this combination is safer and still effective.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
1,000 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have atrial fibrillation, a type of irregular heartbeat.
  • You are taking or starting a blood thinner called a NOAC (like apixaban, rivaroxaban, dabigatran, or edoxaban).
  • You have at least one factor that increases your risk of stomach bleeding, such as being 75 or older, having kidney disease, taking aspirin or other antiplatelet drugs, using pain relievers like ibuprofen, having had a stomach ulcer or bleeding before, or having a high bleeding risk score.
  • You do not have active stomach bleeding, severe liver disease, or a life expectancy of less than one year.
  • You are not already required to take a similar stomach-protecting drug (PPI) long-term.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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