Cellular therapy for aplastic anemia
Part of Blood & lymphatic clinical trials.
This study tests an experimental treatment made from special immune cells designed to help your body fight aplastic anemia. It may be an option if you still need blood transfusions despite standard treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years of age or older.
- You have been diagnosed with aplastic anemia.
- You still need blood transfusions after at least one prior treatment, or you couldn't tolerate the standard treatment.
- You are not HIV positive.
- You do not have an uncontrolled infection or other serious illness.
- You are not pregnant or breastfeeding, and agree to use birth control if applicable.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new medicine called CM313 for people with aplastic anemia that has not responded to standard treatments or has come back. The medicine is given as an injection under the skin and may help your bone marrow make more blood cells.
This study is testing whether a stem cell transplant (from a matched relative, unrelated donor, or half-matched donor) can help adults aged 40–60 with severe aplastic anemia that didn't get better or came back after standard treatments.
This trial tests a new approach: first, you receive a specially engineered immune cell treatment (CD7 CAR-T) to help prepare your body, then a stem cell transplant from a relative. It's designed for people with severe aplastic anemia who cannot have or choose not to get a standard transplant.
This study tests a new antibody drug (anti-CD38) for people with severe aplastic anemia that has not responded to or has come back after standard treatments. The goal is to see if this drug can help improve blood counts when other options have failed.
This trial tests a new way of using a mix of donor stem cells (from a half-matched family member and a cord blood unit) to treat aplastic anemia, a condition where the bone marrow stops making enough blood cells. The goal is to see if this transplant approach is safe and helps rebuild healthy blood cells.
This trial compares two standard treatments for severe aplastic anemia (a condition where the bone marrow stops making enough blood cells). One treatment is a stem cell transplant from a donor, and the other is a drug therapy that suppresses the immune system. The goal is to see which works better as a first treatment.
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