Combination therapy for high-risk acute myeloid leukemia
Treatments studied
Part of Blood & lymphatic, Cancer clinical trials.
This trial tests a new drug called APG1252 combined with azacitidine (AZA) for people with high-risk AML or certain related blood cancers. The goal is to see if the combination works better than standard treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have been diagnosed with high-risk AML or a related bone marrow disorder that has come back or not responded to treatment, or you have a specific subtype (like AML-M6, AML-M7, or with MECOM gene changes) without prior therapy.
- Your liver and kidneys are working well enough (specific tests required).
- You are able to take care of yourself (ECOG score of 0–2).
- If you could become pregnant, you agree to use effective birth control during the study and for a period after.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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