Steroid injection during stroke clot removal surgery
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests whether injecting a steroid (methylprednisolone) directly into brain blood vessels after removing a stroke clot helps reduce brain swelling and improve recovery. You would be eligible if you had a large clot stroke in the front part of your brain that was successfully removed within the past 24 hours.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 18–80 years old
- Stroke caused by a large blood clot in the front of the brain, confirmed by imaging (CT, MRI, or angiography)
- Successfully had the clot removed by endovascular thrombectomy (a minimally invasive surgery)
- Stroke severity score (NIHSS) of 6 or higher
- No active bleeding in the brain on imaging
- Able to sign consent and complete follow-up visits
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether injecting a blood thinner called tirofiban directly into brain blood vessels during a stroke procedure helps prevent clots from forming again. If you've had a stroke caused by a large clot in your brain that was successfully removed, this study may help protect your recovery.
This trial tests if giving a steroid (methylprednisolone) directly into the brain artery after successful clot removal improves recovery. It is for people who had a large stroke in the front part of the brain and got the clot out within 24 hours.
This study tests if adding a steroid medication (methylprednisolone) to the standard procedure of removing a large blood clot from the brain can improve recovery for people with a severe ischemic stroke. It is for adults who can have the clot removal procedure and have a large area of brain damage.
This study tests if adding the steroid methylprednisolone to the standard clot-removal procedure (thrombectomy) can improve recovery for people with a large ischemic stroke, compared to thrombectomy alone.
This trial tests if the steroid methylprednisolone helps people who have had a major stroke and also have low infection-fighting white blood cells (lymphocytes). It is for patients who are getting a procedure to remove the clot (thrombectomy) within 24 hours of the stroke.
This study tests whether a steroid called methylprednisolone, given soon after a flow diverter stent is placed, can help reduce inflammation and improve outcomes for people with an unruptured brain aneurysm. It is for patients who are already scheduled for this stent procedure.
Hear when a new Ischemia Stroke trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.