Testing a medication after clot removal for major stroke
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This study tests whether a medication called a GLP-1 receptor agonist (a type of drug used for diabetes) can improve recovery after a major stroke that was treated with a procedure to remove the blood clot. The goal is to see if this drug helps reduce further brain damage and improve outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be at least 18 years old.
- Your stroke must be from a blockage in a large artery in the brain, and you must have had a procedure to remove the clot.
- The stroke must have started within the last 24 hours before you would be treated.
- Your stroke symptoms must be at least moderately severe, based on a standard stroke scale score of 6 or higher.
- You must not have received IV clot-busting medication (like alteplase or tenecteplase) for this stroke.
- You must be generally healthy before the stroke (able to do your own daily activities without significant help).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether a drug called semaglutide (usually used for diabetes) can improve brain recovery when given after a stroke clot removal procedure. You may receive the drug or a placebo, and researchers will check your neurological outcomes.
This trial tests whether giving a clot-busting drug (alteplase) directly into the brain artery after a successful clot removal improves recovery in people with severe stroke. It is for patients who have had a thrombectomy and still have a large blocked artery in the front of the brain.
This trial tests giving a clot-dissolving medicine (rhPro-UK) through a vein before a procedure to remove a large blood clot in the brain. It is for people who had a stroke 4.5 to 24 hours ago and are already scheduled for clot removal. The goal is to see if the medicine helps improve blood flow and outcomes.
This trial tests if removing a large blood clot from the brain up to 3 days after a stroke improves recovery compared to standard medical care alone. It is for patients who have a severe stroke and are otherwise healthy enough for the procedure.
This Phase 2 study tests whether a semaglutide injection given under the skin soon after an acute ischemic stroke can improve recovery. It may help reduce disability, especially if treatment starts within about 4.5 hours of symptom onset.
This trial tests whether using a balloon or stent to reopen a blocked artery in the brain, after the initial clot removal procedure, is safe and effective for people who still have poor blood flow. It aims to improve recovery after a stroke caused by hardening of the arteries.
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