Steroid plus clot removal for large stroke
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests whether adding a steroid medicine (methylprednisolone) to the standard procedure to remove a blood clot (thrombectomy) can improve recovery in people with large, severe strokes. The study aims to see if the steroid helps reduce brain swelling and improves outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 85 years old.
- You had a severe ischemic stroke (a blockage in a blood vessel in the brain) within the last 24 hours.
- Your doctor found a blockage in a large artery in your brain using a CT or MRI scan, and you are planning to have surgery to remove it (called a thrombectomy).
- Your stroke is 'large,' meaning there is a big area of damage on your brain scan.
- You must not have certain bleeding risks, severe infections, or allergies to steroids or contrast dye.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if a procedure to remove a large blood clot from the brain (called a thrombectomy) can help people with severe strokes who have a large damaged area. It is for people who can be treated within 24 hours of their stroke starting.
This trial tests whether adding a steroid (methylprednisolone) to the standard clot-removal procedure can improve recovery in people with a severe, large stroke. It aims to reduce brain swelling and improve outcomes after the procedure.
This trial tests whether adding a steroid called methylprednisolone during a procedure to place a stent for an unruptured brain aneurysm can reduce side effects and improve recovery. It's a phase 4 study, meaning the drug is already approved for other uses, and researchers are checking if it works well for this specific situation.
This trial tests if giving a steroid (methylprednisolone) directly into the brain artery after successful clot removal improves recovery. It is for people who had a large stroke in the front part of the brain and got the clot out within 24 hours.
This trial tests whether injecting a steroid (methylprednisolone) directly into brain blood vessels after removing a stroke clot helps reduce brain swelling and improve recovery. You would be eligible if you had a large clot stroke in the front part of your brain that was successfully removed within the past 24 hours.
This trial tests if the steroid methylprednisolone helps people who have had a major stroke and also have low infection-fighting white blood cells (lymphocytes). It is for patients who are getting a procedure to remove the clot (thrombectomy) within 24 hours of the stroke.
Hear when a new Ischemic Stroke, Acute trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.