Steroid plus clot removal for large stroke
Part of Brain & nervous system, Heart & circulation clinical trials.
This study tests if adding the steroid methylprednisolone to the standard clot-removal procedure (thrombectomy) can improve recovery for people with a large ischemic stroke, compared to thrombectomy alone.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have had a large stroke (caused by a blockage in a major brain artery) within the last 24 hours
- You are eligible for a procedure called a thrombectomy to remove the clot
- You do not have a bleeding problem or take blood thinners that can't be stopped
- You are not allergic to steroids or the dye used in scans
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if giving a steroid (methylprednisolone) directly into the brain artery after successful clot removal improves recovery. It is for people who had a large stroke in the front part of the brain and got the clot out within 24 hours.
This trial tests a new medicine (glenzocimab) given along with standard clot-removal procedure for people who had a stroke with a large area of brain damage. The goal is to see if the medicine helps improve recovery.
This study tests whether adding a drug called human urinary kallidinogenase to standard clot-removal therapy helps people recover better after a large-vessel stroke. If you qualify, you would receive the drug or a placebo by IV along with the procedure, and doctors will monitor your recovery.
This trial tests giving a clot-dissolving medicine (rhPro-UK) through a vein before a procedure to remove a large blood clot in the brain. It is for people who had a stroke 4.5 to 24 hours ago and are already scheduled for clot removal. The goal is to see if the medicine helps improve blood flow and outcomes.
This study tests if adding a steroid medication (methylprednisolone) to the standard procedure of removing a large blood clot from the brain can improve recovery for people with a severe ischemic stroke. It is for adults who can have the clot removal procedure and have a large area of brain damage.
This study tests whether a steroid called methylprednisolone, given soon after a flow diverter stent is placed, can help reduce inflammation and improve outcomes for people with an unruptured brain aneurysm. It is for patients who are already scheduled for this stent procedure.
Hear when a new Acute Ischemic Stroke trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.