Clin2
NCT07576543Possibly a fitNot yet recruiting

Long-term memory and thinking after surgery in older adults

Older PatientsSurgeryDexmedetomidineEsketamineTranscranial Direct Current StimulationCognitive FunctionSurvival

Part of Brain & nervous system, Mental health, Pain clinical trials.

This study looks at combining two treatments—a sedative drug and a mild brain stimulation technique—to see if they can help reduce confusion or memory problems that can happen after surgery in older people. It might help you if you have mild cognitive issues before your surgery.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
1,996 people
Ages
65 years and older
Study type
Interventional

Who can take part

  • You are between 65 and 90 years old.
  • You have mild to moderate memory or thinking problems before surgery (scoring 2 or less on a short memory test).
  • You are having non-cardiac, non-brain surgery under general anesthesia that is expected to last more than 1 hour.
  • You are expected to need a patient-controlled pain pump after surgery.
  • You have not had conditions like schizophrenia, epilepsy, Parkinson's, or brain surgery, and do not have metal implants in your head or neck.
  • Your heart, liver, and kidney function are within safe limits for the study.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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