Brain Recovery Study After Surgery in Older Adults
Part of Brain & nervous system, Mental health, Pain clinical trials.
This study follows older adults aged 65–90 who have some memory concerns before surgery. It tests whether a combination of two medications (dexmedetomidine and esketamine) plus a non-invasive brain stimulation technique called tDCS can help prevent or reduce thinking and memory problems that sometimes happen after surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 65 and 90 years old
- You have mild-to-moderate memory or thinking concerns before surgery (screened by a short test)
- You are scheduled for planned surgery (not emergency) lasting more than 1 hour, not on the heart or brain
- You will need pain medication through an IV pump that you can control after surgery
- You do not have a history of schizophrenia, epilepsy, Parkinson's disease, or brain injury/surgery
- You do not have metal implants in your brain, spine, or inner ear, and your skin on your head is healthy
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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