Medication combination for mood after urine tube surgery
Part of Mental health clinical trials.
This study tests whether combining two medications, dexmedetomidine and esketamine, given during and after surgery can reduce feelings of depression and anxiety after a procedure to repair a narrowed urine tube. It may help improve your mood and recovery after surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have a narrowing of the urine tube (ureteral stricture) and are having surgery to fix it
- You are scheduled to receive a patient-controlled pain pump after surgery
- You do not have certain mental health or nervous system conditions like schizophrenia, epilepsy, Parkinson's disease, or severe muscle weakness
- You do not have severe heart problems or conditions that affect your heart rhythm
- You are not allergic to the study drugs (dexmedetomidine or esketamine)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether two medicines, dexmedetomidine and esketamine, can reduce discomfort from a urinary catheter after bladder or prostate surgery. If you are having this type of surgery and need a catheter, this trial may help find a better way to manage that discomfort.
This trial tests if giving two medicines, dexmedetomidine and esketamine, during and after surgery can help you feel better and recover more comfortably. It is for adults having general anesthesia for at least one hour who will use a patient-controlled pain pump afterward.
This study tests whether a combination of two medicines, dexmedetomidine and esketamine, can help improve sleep problems after major non-heart surgery. You may be eligible if you are having planned surgery lasting at least one hour and will use a pain pump after surgery.
This study tests whether combining two medicines, dexmedetomidine and esketamine, during spine surgery can help prevent chronic pain that sometimes continues for months after surgery. If you are having spine surgery and will use a pain pump afterward, this trial might be a good fit for you.
This study tests a combination of two medicines given through an IV after spine surgery to see if it controls moderate to severe pain better. It may help reduce pain and improve recovery.
This study tests a combination of two medicines (dexmedetomidine and esketamine) to help ICU patients who are on a breathing machine feel calm and have less pain. The goal is to find a safe and effective way to keep patients comfortable while they recover.
Hear when a new Ureteral Stricture trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.