Clinical trials
Hepatic Encephalopathy clinical trials
Below are recruiting hepatic encephalopathy clinical trials, each written for real people, not researchers. We’re tracking 18 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04096014Recruiting
Protein supplement at night to prevent repeat brain episodes
This study tests whether taking extra protein in the late evening or early morning can lower the chance of being readmitted for hepatic encephalopathy, a brain problem that can happen with liver disease. It may help by supporting safer nutrition and reducing the risk of another hospitalization.
Cleveland, OhioAges 18–75 - NCT04161053RecruitingPhase 3
Nitazoxanide to prevent repeat liver brain episodes
This Phase 3 trial tests whether nitazoxanide can help stop hepatic encephalopathy (a “liver-to-brain” confusion problem) from coming back. It’s for adults with cirrhosis who have had at least one past episode, aiming to improve safety and prevent recurrence.
TantaAges 20–65 - NCT06425380Recruiting
Resistant potato starch for liver cirrhosis and confusion
This study is testing whether a special type of starch (resistant potato starch) can help people with cirrhosis who have had episodes of confusion from liver problems. It may help by changing the bacteria in your gut, which could reduce the risk of future confusion episodes.
Rochester, MinnesotaAges 18–99 - NCT07683936RecruitingEarly Phase 1
Fecal transplant for brain issues after liver procedure
This trial tests if transferring healthy bacteria into your gut (fecal microbiota transplant) can help people who still get confusion episodes (hepatic encephalopathy) even after a TIPS procedure and while on standard medications like lactulose and rifaximin.
Xi'anAges 18–75 - NCT05433948Enrolling by invitation
Testing ways to diagnose mild brain changes in liver disease
This study looks at how well simple brain tests can detect early (minimal) thinking changes related to liver cirrhosis. It may help doctors spot these changes sooner and diagnose the condition more accurately.
EsbjergAges 18–90 - NCT07046429Recruiting
Melatonin for sleep and brain health in cirrhosis
This study tests whether melatonin (a natural sleep hormone) can improve sleep and thinking abilities in people with cirrhosis and liver-related brain fog. It aims to see if better sleep leads to clearer thinking.
New York, New YorkAges 18 years+ - NCT06483737Recruiting
Albumin for cirrhosis patients with hepatic encephalopathy
This trial tests whether giving human albumin through a vein can help people with liver cirrhosis who have confusion or drowsiness from a condition called hepatic encephalopathy. It is for patients with low albumin levels.
Shenyang, LiaoningAges 18 years+ - NCT06538077RecruitingPhase 4
BCAA vs. Rifaximin to Prevent Recurrent Hepatic Encephalopathy
This trial compares two treatments—BCAA supplements and rifaximin—to see which is better at preventing another episode of confusion or coma in people with cirrhosis who have already had one. If you qualify, you would receive one of these treatments for several months.
ChandigarhAges 18–65 - NCT04073290RecruitingPhase 4
Rifaximin and lactulose to prevent confusion after TIPS
This trial studies whether taking rifaximin plus lactulose can prevent a brain problem called hepatic encephalopathy (confusion) after TIPS, a procedure to reduce pressure in the liver. It may help people who are having TIPS planned and are at risk of this complication.
LeuvenAges 18–80 - NCT06052176RecruitingPhase 2
Albumin for better thinking in liver disease
This trial tests if weekly albumin infusions can improve thinking problems (called hepatic encephalopathy) in people with cirrhosis. You may be eligible if you have cirrhosis, some memory or concentration issues, and have been taking lactulose or rifaximin for at least a month.
Richmond, VirginiaAges 18 years+ - NCT07349654Recruiting
New stent method to reduce brain fog after TIPS procedure
This trial tests a modified stent placement technique during TIPS (a procedure to lower blood pressure in the liver) to see if it helps prevent confusion and memory problems that can happen afterward.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT06953921Recruiting
Liver disease and confusion: does albumin level matter?
This study looks at whether low albumin levels in the blood are linked to more severe confusion caused by liver disease. It may help doctors understand how to better manage hepatic encephalopathy.
SohagAges 18 years+ - NCT06619106Recruiting
Screening tool for minimal hepatic encephalopathy
This study tests a new cognitive tool to quickly and reliably detect minimal hepatic encephalopathy, a subtle brain change that can occur in people with liver disease. If you have a liver condition like fibrosis or cirrhosis and are already scheduled for a full evaluation (neuropsychological tests, MRI, EEG, and blood ammonia), this tool could help simplify future screening.
ParisAges 18–70 - NCT04014413Recruiting
Fecal transplant for gut and immune-related conditions
This trial studies whether fecal microbiota transplantation (FMT)—a medical procedure using stool from a screened donor to restore gut bacteria—can improve safety and outcomes for people with certain bowel, immune, and metabolic conditions. It may help if your symptoms are thought to be related to an unhealthy gut microbiome, though eligibility is broad and depends on specific safety factors.
Hong Kong, ShatinAges Any age - NCT06808074RecruitingPhase 4
Inhaled amikacin to prevent pneumonia in cirrhosis patients on ventilators
This trial tests whether inhaling an antibiotic called amikacin can prevent ventilator-associated pneumonia in patients with severe liver disease (cirrhosis) who are on a breathing machine. If you or your loved one is in the ICU with liver issues and needs a ventilator, this study may help reduce the risk of a serious lung infection.
Hyderabad, TelanganaAges 18 years+ - NCT03267615Recruiting
Study in advanced liver scarring using pressure and stiffness tests
This study looks at people over 18 who have advanced, long-term liver scarring. It uses specialized measurements of liver stiffness and pressure to confirm eligibility and may help doctors better understand this condition.
ViennaAges 18–100 - NCT07418008Recruiting
Thinking and memory study for people with liver cirrhosis
This study is creating a new test to measure thinking and memory problems in people with liver cirrhosis. It may help doctors find these problems earlier.
Ambāla, HaryanaAges 18–75 - NCT07521332RecruitingPhase 4
Testing Apixaban to Prevent Bleeding Complications in Cirrhosis
This study tests whether a blood thinner called apixaban can safely prevent dangerous bleeding in people with cirrhosis (liver scarring) who have portal hypertension (high blood pressure in veins leading to the liver). The goal is to see if it reduces bleeding risk without causing excessive bleeding.
Hyderābād, SindhAges 18 years+
Hear when a new Hepatic Encephalopathy trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Hepatic Encephalopathy trials by city
Studies with a site in or near these metro areas.
Common questions
- Are there clinical trials for hepatic encephalopathy?
- Yes. Clin2 currently lists 18 recruiting hepatic encephalopathy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hepatic encephalopathy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hepatic encephalopathy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.