Sentinel node biopsy after chemotherapy for node-positive breast cancer
Part of Cancer, Skin clinical trials.
This trial tests a less extensive armpit surgery after chemotherapy for breast cancer that had spread to lymph nodes. The goal is to see if removing only the sentinel nodes (guided by blue dye) is safe and effective when nodes appear clear after treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman aged 18 to 70, newly diagnosed with breast cancer that has not spread far.
- A needle biopsy confirmed cancer in an armpit lymph node (axillary node positive).
- You must receive standard chemotherapy or hormone therapy before surgery (neoadjuvant therapy) for about 6 or 8 cycles.
- After neoadjuvant therapy, ultrasound shows the armpit nodes look normal (cN0).
- You are willing to have a surgery that removes only a few sentinel lymph nodes (guided by blue dye) plus standard removal of armpit lymph nodes.
- No serious heart, lung, liver, or kidney problems, and no poorly controlled diabetes.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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