Clin2
NCT07533396Likely a fitNot yet recruiting

Understanding tooth nerve inflammation through dental samples

Pulpal Inflammation

Part of Mouth & dental clinical trials.

This study looks at the tissue inside your tooth (the pulp, or nerve) to better understand inflammation. If you're having a root canal or tooth removal as part of your regular dental care, the dentist will collect a small sample of that tissue for research. This might help improve future treatments for tooth pain and infection.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
1,200 people
Ages
18 years and older
Study type
Observational

Who can take part

  • You are 18 years or older.
  • You are scheduled for a routine dental procedure that removes the pulp (nerve) of a tooth, such as a root canal or tooth extraction.
  • You have not taken anti-inflammatory medication (like ibuprofen or aspirin) within 12 hours before the procedure.
  • You are not under legal guardianship or curatorship.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07450235Not yet recruiting
Saliva and tooth pulp markers for tooth nerve pain

This study looks at natural healing markers in saliva, gum fluid, and tooth pulp to understand tooth nerve pain better. It compares people with tooth nerve pain to healthy people to find ways to improve treatment.

Nantes, Loire-Atlantique
NCT07532200Recruiting
Pain genes and inflammation in tooth root canal treatment

This research study examines how your genes affect pain and inflammation when you have a painful tooth that needs root canal treatment. By studying these responses, researchers hope to better understand why some people experience different levels of pain during dental procedures.

New Delhi, National Capital Territory of Delhi
NCT05964933Enrolling by invitation
Pulpotomy vs root canal for painful nerve inflammation

This trial compares two treatments for a tooth nerve that is very inflamed and causing lingering pain: a pulpotomy versus a full root canal. It may help you choose the approach that best relieves symptoms and supports healing for the right kind of tooth.

Singapore
NCT06938191Not yet recruiting
Comparing tooth fluid markers for pulp inflammation

This study looks at certain proteins in the fluid around teeth and inside the tooth to see if they can tell the difference between healthy teeth and teeth with severe pulp inflammation (pulpitis). It may help find better ways to diagnose tooth pain.

NCT07171229Not yet recruiting
Checking inflammation markers and success of baby tooth nerve treatment

This study looks at whether certain substances in the blood (called cytokines) can tell how inflamed the tooth's pulp is, and whether that affects how well a pulpotomy works. A pulpotomy is a procedure that removes the infected part of the nerve inside a baby tooth to save the tooth and avoid early loss.

Cairo
NCT07289074Not yet recruiting
Inflammation markers in painful teeth

This study looks at levels of two inflammation markers in the fluid around a painful tooth. It aims to see if these markers are higher when the tooth's nerve is damaged and there is an infection at the root tip, which may help in diagnosing and treating such pain.

Cairo, Cairo Governorate

Hear when a new Pulpal Inflammation trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.