New clot-busting medication for stroke in the extended time window
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests a new medication called rhTNK-tPA for treating acute ischemic stroke (a clot in the brain) up to 24 hours after symptom onset. The study uses simplified imaging to determine eligibility and aims to help patients recover better outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 18 years old
- You had a stroke caused by a blood clot in the front part of your brain within the last 4.5 to 24 hours (or woke up with stroke symptoms)
- Your stroke severity score (NIHSS) is between 6 and 25
- Your initial CT scan shows limited damage and no bleeding in or around your brain
- You were living independently before your stroke (able to care for yourself)
- You do not have bleeding problems, recent major surgery, uncontrolled high blood pressure, or active bleeding
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests a clot-dissolving medication called rhTNK-tPA for people who had a stroke 4.5 to 24 hours ago. It aims to help those with certain types of blockages in the brain who are still having moderate to severe symptoms.
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