Testing Common Sleep Medications for Insomnia
Treatments studied
Part of Brain & nervous system, Mental health clinical trials.
This study compares how well different over-the-counter and prescription sleep medications work for insomnia. Researchers will guide you through trying medications one at a time to find what works best for your sleep problems.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old
- You have been diagnosed with insomnia disorder and have trouble falling or staying asleep at least 3 nights per week for 3+ months
- You are willing to stop all sleep medications for 2 weeks before the study starts
- You do not have other sleep disorders like sleep apnea, circadian rhythm problems, or work night shifts
- You have a smartphone or computer and can communicate in English
- Your doctor agrees that you are healthy enough to participate
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a behavioral (non-medication) program to help people with chronic insomnia sleep better. It may help if you regularly use sleep medications but still struggle with staying asleep or falling asleep.
This study tests an investigational medication to help people with insomnia fall asleep faster and stay asleep longer. If you have trouble sleeping despite trying other treatments, this trial may offer a new option.
This study tests a sleep medication called ramelteon for people with chronic insomnia. If you qualify, you may receive the study drug or a placebo, and researchers will monitor your sleep over several weeks to see if it helps you fall asleep faster and sleep longer.
This trial tests a new inhaled form of melatonin to help adults aged 55 and older with insomnia fall asleep faster. It compares the inhaled melatonin to a placebo to see if it improves sleep and is safe.
This trial compares two treatments for chronic insomnia: cognitive behavioral therapy (CBT-I) and a medication called lemborexant. It aims to find which works better for different types of insomnia. You may qualify if you have ongoing trouble sleeping and are not taking other sleep aids.
This study tests whether adding a melatonin supplement to a type of talk therapy for insomnia (called CBT-I) helps older adults sleep better. It aims to improve sleep quality and reduce insomnia symptoms.
Hear when a new Insomnia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.