Rapid Methadone Restart After Short Break
Treatments studied
Part of Mental health clinical trials.
This study helps people with opioid addiction quickly restart methadone treatment after stopping for a few days. Researchers want to see if restarting methadone safely can reduce fentanyl use and prevent overdose.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 19 years old
- You have opioid use disorder (addiction to opioids like heroin or prescription painkillers)
- You were previously stable on methadone for at least 5 days before stopping
- You have missed 4–8 doses of methadone in a row and want to restart
- You have used more fentanyl since stopping methadone
- Your urine tests positive for fentanyl at screening
- Your heart's electrical activity (ECG) shows a QTc measurement under 500 milliseconds
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This Phase 2 study compares a rapid way to start buprenorphine/naloxone versus the standard way, for people with opioid use disorder. It aims to see whether the faster start is safe and works well enough to help people begin treatment sooner.
This study tests a faster way to start buprenorphine (a medication for opioid use disorder) by using naloxone to briefly trigger mild withdrawal. This could help people get started on treatment more comfortably and quickly.
This trial tests a way to quickly start buprenorphine (a medication for opioid addiction) in an outpatient clinic for people who use fentanyl. It aims to make starting treatment easier and faster, without needing to go through full withdrawal first.
This study helps people who are in the hospital for opioid use disorder start a medication like methadone or buprenorphine after they leave the hospital. It aims to make starting treatment easier and improve recovery.
This study compares two medications, methadone and buprenorphine, to see which helps people stay in treatment for opioid use disorder. You may be eligible if you are starting a new treatment episode.
This study uses MRI scans over time to track brain changes in people with opioid use disorder who recently started methadone treatment. You can help researchers understand recovery patterns if you are early in your methadone journey and can commit to repeated visits.
Hear when a new Opioid Use Disorder trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.