Clin2
NCT07548489Likely a fitNot yet recruiting

Phenobarbital for agitated delirium

Agitated DeliriumDelirium Confusional StateDelirium in the Intensive Care UnitHyperactive Delirium

Treatments studied

Part of Brain & nervous system clinical trials.

This trial tests whether the medication phenobarbital can help calm people with agitated or hyperactive delirium. It may offer an option for managing these symptoms in a hospital setting.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
150 people
Ages
21 years and older
Study type
Interventional

Who can take part

  • You are an adult who has been diagnosed with agitated or hyperactive delirium (a state of confusion with restlessness or agitation).
  • You are not pregnant.
  • You are not currently incarcerated.
  • You do not have severe liver disease.
  • You have no known allergy or previous bad reaction to phenobarbital or antipsychotic drugs.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07428681Not yet recruiting· Phase 4
Lorazepam to prevent delirium in intensive care patients

This study tests whether giving a low dose of lorazepam, a calming medicine, can help prevent delirium (confusion and agitation) in patients newly admitted to the intensive care unit (ICU). It may help patients recover more smoothly.

NCT07485244Recruiting
EEG brain monitoring in ICU patients at risk for delirium

This study uses a simple headband (EEG) to monitor brain activity in ICU patients who are at high risk for delirium. The goal is to see if the EEG can help detect delirium earlier, so doctors can provide better care.

Nashville, Tennessee
NCT07542990Not yet recruiting· Phase 3
Sedation drug for children on breathing machines in intensive care

This study tests a drug called dexmedetomidine to help sedate children who need a breathing machine for more than 12 hours. It may reduce confusion (delirium) compared to usual sedatives.

Angers
NCT05431595Recruiting· Phase 2/Phase 3
Test a less sedating plan for agitated delirium in cancer

This study looks at whether using certain sleep/behavior medicines (called neuroleptics) with anti-seizure medicines can calm agitation from delirium without needing as much of the usual “neuroleptic” medicines. It may help people with advanced cancer who are confused and very restless or hard to settle.

Houston, Texas
NCT06752616Recruiting· Phase 2/Phase 3
Study on calming severe agitation in psychiatric emergency rooms

This trial tests two different medications to quickly calm severe agitation in people admitted to a psychiatric emergency room. You may be able to join if you are extremely agitated and need urgent medication to help you settle down.

Copenhagen N
NCT06993194Not yet recruiting
Comparing two medicines for calming ICU patients with brain injury

This study tests two medications, haloperidol and dexmedetomidine, to see which works better for reducing confusion and agitation in patients who are on a breathing machine after a traumatic brain injury. If you or a loved one is in the ICU with a brain injury and is restless or confused, this trial may help find better ways to manage those symptoms.

Hear when a new Delirium Confusional State trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.