Clin2
NCT07550595Possibly a fitNot yet recruiting

Antibiotic for serious heart infections

Infective EndocarditisCardiac Device InfectionGram-positive Bacterial Infections

Part of Heart & circulation, Infections clinical trials.

This study tests a new antibiotic called oritavancin for treating serious heart infections caused by certain bacteria. It may offer a simpler treatment option for patients who are already on antibiotics and stable.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
20 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • 18 years or older
  • Currently hospitalized for a heart infection (like endocarditis or an infection of a heart device)
  • A bacteria known as Gram-positive must be found in blood or tissue samples
  • No fever for at least 24 hours, and blood cultures clear for at least 24 hours
  • On effective antibiotics for at least 24 hours but no more than 14 days
  • No severe kidney or liver problems, no prosthetic heart valve, and not pregnant or breastfeeding

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07013552Not yet recruiting
Antibiotic treatment for heart device infections

This study tests a new antibiotic called oritavancin for treating skin infections at the site of heart devices like pacemakers or defibrillators, especially when caused by drug-resistant bacteria. The goal is to see if this once-daily antibiotic works as well as the standard treatment.

Katowice, Silesian Voivodeship
NCT07345325Recruiting· Phase 3
Comparing antibiotic treatments for heart valve infections

This trial tests whether a treatment without rifampin works as well as one with rifampin for a type of heart valve infection caused by staph bacteria. It aims to find a simpler and safer option for patients with an infected artificial heart valve.

Aix-les-Bains
NCT04647331Recruiting
Study antibiotic levels in heart valve infection

This trial measures how your body handles certain intravenous antibiotics used for endocarditis, an infection of the heart valves. It may help doctors understand the best antibiotic dosing for people with valve infections.

Gothenburg
NCT07858526Not yet recruiting
Optimised dalbavancin for serious bacterial infections

This study tests a better way to give a long-acting antibiotic called dalbavancin for serious bacterial infections. Dalbavancin is given as an infusion and may allow you to leave the hospital sooner while still completing your antibiotic treatment.

Sydney, New South Wales
NCT07699211Not yet recruiting· Phase 3
Dalbavancin for heart valve infections

This study tests a new antibiotic called dalbavancin for treating infections of the heart valves. It may offer a simpler treatment option with fewer hospital visits.

Freiburg im Breisgau, Baden-Wurttemberg
NCT05398679Recruiting· Phase 4
Oral antibiotics versus IV antibiotics after heart infection

This trial compares taking antibiotics by mouth versus receiving antibiotics through a vein (outpatient IV) for an infection of the heart valve. It’s designed to see whether the oral option can work as well and safely, especially after initial treatment and surgery if needed.

Alicante, Alicante

Hear when a new Infective Endocarditis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.