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NCT07552506Possibly a fitNot yet recruiting

Goserelin to preserve ovarian function in aplastic anemia stem cell transplant patients

Aplastic Anaemia (AA)Allogeneic Haematopoietic Stem Cell TransplantationOvarian Insufficiency

Part of Blood & lymphatic clinical trials.

This study tests whether a medication called goserelin (which temporarily 'puts the ovaries to sleep') can help protect ovarian function in women with aplastic anemia who are having a stem cell transplant. The goal is to see if it helps preserve the chance of getting your period back after the transplant.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
132 people
Ages
14 years to 50 years
Study type
Interventional

Who can take part

  • You have been diagnosed with severe aplastic anemia (a bone marrow disorder) and are scheduled for a stem cell transplant from a donor.
  • You are a female between 14 and 50 years old and have regular menstrual periods before the transplant.
  • You (or your legal guardian) agree to join the study and sign a consent form.
  • Your doctors expect you to live for more than one year, so there is enough time to see if your periods return.
  • You do not have severe heart, liver, or kidney problems, and you are not allergic to goserelin or similar drugs.
  • You have not already gone through menopause, and you do not have significant gynecological conditions like PCOS or endometriosis.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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