Clin2
NCT07556887Likely a fitRecruiting

Using IMPROVE to Choose Carotid Artery Treatment After Stroke

Carotid Artery Stenosis SymptomaticIschemic Cerebral InfarctionStroke IschemicAtherosclerosesStroke (CVA) or TIAStrokeIntraplaque HemorrhageTIA (Transient Ischemic Attack)

Part of Brain & nervous system, Heart & circulation clinical trials.

This study tests whether a new tool called IMPROVE helps doctors decide if you need surgery or a stent to clear a narrowed carotid artery (a major neck blood vessel) after a recent stroke or mini-stroke. The goal is to better predict which patients will benefit most from this treatment.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
613 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You had a stroke or mini-stroke (TIA) within the last 30 days with mild to moderate disability
  • You have a narrowed carotid artery (30–99% blockage) on the same side as your stroke
  • You are 18 years or older and mentally able to make medical decisions
  • Your doctors believe you are a good candidate for carotid artery treatment (surgery or stent)
  • You are willing to be randomly assigned to either the new IMPROVE method or standard care to decide your treatment
  • You have no heart rhythm problems that could cause blood clots, and your carotid narrowing is from plaque buildup (atherosclerosis), not other causes

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07054060Recruiting
Surgery vs. Stenting for Recent Stroke Symptoms from a Narrowed Carotid Artery

This trial compares two procedures—surgery to remove plaque from a carotid artery or placing a stent to widen the artery—to see which is better for people who recently had warning signs or a small stroke due to a severe blockage. The goal is to find the safest and most effective way to prevent future strokes.

Paris
NCT06767657Recruiting
Immediate vs delayed surgery for recent mini-stroke or mild stroke

This trial compares two approaches for treating a blocked carotid artery after a mini-stroke or mild stroke: surgery done right away (within hours) versus waiting a short while. The goal is to see which timing helps prevent another stroke better.

Florence
NCT07166731Recruiting
Carotid stent vs. medication for recent stroke risk

This trial tests if a carotid artery stent plus medication is better than medication alone at preventing another stroke in people who recently had a stroke or eye blockage caused by a non-narrowing but risky carotid plaque.

Solingen, North Rhine-Westphalia
NCT07839390Not yet recruiting
Comparing medical care with or without a procedure for moderate carotid narrowing

This study compares two approaches for people who have recently had a stroke or mini-stroke caused by a moderately narrowed carotid artery in the neck. Half will get the best medical treatment alone (like clot-preventing medicines and risk-factor management), and the other half will get the same medical treatment plus a procedure to open the narrowed artery (either surgery or a stent). The goal is to see which approach better prevents future strokes.

NCT07803419Not yet recruiting
Restoring blood flow for blocked carotid artery

This trial tests a procedure to reopen a blocked carotid artery in the neck that has caused a stroke or mini-stroke in the last three months. The goal is to improve blood flow to the brain and potentially help with thinking and memory problems.

Beijing, Beijing Municipality
NCT03344276Recruiting
Testing thinking and memory after carotid artery treatment

This study checks how a carotid artery procedure affects thinking and memory. You may be able to join if you’re an adult with significant carotid artery narrowing seen on ultrasound, and you can safely do follow-up MRI scans.

San Diego, California

Hear when a new Carotid Artery Stenosis Symptomatic trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.