Clin2
NCT07572175Possibly a fitNot yet recruiting

Sotagliflozin to prevent heart damage from chemotherapy

Anthracycline-induced CardiotoxicityLymphomaChemotherapyCardiotoxicity

Treatments studied

Part of Blood & lymphatic, Cancer, Heart & circulation, Immune system & allergy, Injuries & trauma clinical trials.

This trial tests whether a medicine called sotagliflozin, typically used for diabetes, can protect the heart during chemotherapy for lymphoma. It may help prevent heart problems that can be a side effect of the cancer treatment.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
60 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older
  • You have been diagnosed with lymphoma (a type of blood cancer)
  • You are scheduled to receive a strong chemotherapy called anthracycline, at a high dose
  • You have a performance status of 0-3 (meaning you are still able to care for yourself, though you may need some help)
  • You have not had this type of chemotherapy before
  • You have not been treated with sotagliflozin or similar medicines in the past

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07852546Not yet recruiting· Phase 3
Linagliptin for heart protection in breast cancer treatment

This trial tests whether taking linagliptin, a diabetes medicine, can help protect the heart during chemotherapy with doxorubicin. It might reduce the risk of heart damage caused by this chemo drug.

Tanta, Elgharbeya
NCT07654426Recruiting· Phase 2
Heart protection during lymphoma chemotherapy

This trial tests if a heart-protecting drug (dexrazoxane) can prevent heart damage in people getting chemotherapy for certain types of large B-cell lymphoma. It is for patients who already have heart risk factors or a history of heart failure.

Boston, Massachusetts
NCT05223413Recruiting
Remote arm treatment to protect the heart during chemo

This trial studies whether a simple “remote conditioning” treatment on the arm can help protect the heart while you receive chemotherapy that includes anthracyclines. If you’re at higher risk for heart damage from chemo, this may reduce risk and help monitor heart function over time.

Aarhus
NCT05465031Recruiting· Phase 4
Testing heart-protection medicine during breast cancer treatment

This trial tests sacubitril/valsartan to help prevent heart weakness (cardiotoxicity) caused by breast cancer treatments like anthracyclines and/or anti-HER2 drugs. If you qualify, you may be offered this heart-protection medicine while your cancer is treated.

Opole, Opole Voivodeship
NCT05989347Recruiting· Phase 1
Dapagliflozin with chemo for breast cancer

This trial tests whether adding the drug dapagliflozin (a pill that lowers blood sugar) to standard chemotherapy before breast cancer surgery can improve outcomes. It is for women with high insulin levels and a higher BMI who are about to start chemotherapy.

New Haven, Connecticut
NCT07245069Recruiting· Phase 2
Can dapagliflozin protect the heart during breast cancer chemo?

This trial tests if the drug dapagliflozin can prevent heart damage caused by anthracycline chemotherapy in breast cancer patients. It aims to see if taking the drug during chemo helps keep your heart healthy.

Ljubljana

Hear when a new Anthracycline-induced Cardiotoxicity trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.