GLP1 Receptor Blood Test in Advanced Leg Artery Disease
Part of Heart & circulation clinical trials.
This study looks at a specific receptor (GLP1R) on blood cells in people with advanced peripheral artery disease (PAD) who do not have diabetes. The goal is to understand if this receptor could be a target for future treatments to improve blood flow and save limbs.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 40 years old or older.
- You have a condition called peripheral artery disease (PAD) — either pain when walking due to blocked leg arteries, or more severe symptoms like pain at rest and sores on your leg or foot.
- You do not have diabetes (type 1 or type 2).
- You are not currently taking medications called SGLT2 inhibitors or GLP-1 receptor agonists (these are diabetes drugs).
- You do not have an active infection, cancer, or a condition that weakens your immune system (like an organ transplant or autoimmune disease requiring immunosuppressants).
- You do not have kidney failure that requires dialysis.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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