Nerve blocks for pain relief after knee replacement
Part of Pain clinical trials.
This trial tests two types of numbing injections (nerve blocks) around the knee to help manage pain after total knee replacement surgery. The goal is to see if these injections reduce pain and improve recovery compared to standard pain treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older
- You are scheduled for elective (planned) total knee replacement on one knee only
- You are willing and able to receive spinal anesthesia (numbing medicine injected into your spine)
- You do not have a history of severe allergic reactions to local anesthetics, gelatin, or chlorhexidine (a disinfectant)
- You do not have a bleeding disorder and can safely stop blood-thinning medications if needed
- You do not have an active infection at the injection site or sepsis (blood infection)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two different nerve-blocking anesthesia techniques to see which one controls pain better after knee replacement surgery. Both methods are designed to numb the area around your knee so you need less pain medication afterward.
This study compares two types of nerve blocks for pain control after knee replacement surgery. One uses a standard block near the knee, and the other adds a second block to see if it improves pain relief and recovery.
This trial tests if adding extra nerve blocks (sciatic, BiFeS, or IPACK) to the usual adductor canal block can reduce pain after total knee replacement. The goal is to find a better way to manage pain and improve recovery.
This study compares two ways to manage pain after knee replacement surgery: local numbing medicine injected into the knee versus numbing several nerves in the leg. The goal is to find which method provides better pain control and recovery.
This study tests whether blocking a specific nerve in the knee can reduce pain and improve recovery after total knee replacement surgery. You would receive this nerve block alongside standard anesthesia to see if it helps you need fewer pain medications afterward.
This study compares two types of numbing injections (nerve blocks) used during knee replacement surgery to see which one helps your thigh muscle recover strength faster. Both are standard care options; the trial tests which works better for early movement after surgery.
Hear when a new Postoperative Pain Following Knee Arthroplasty trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.