Esketamine to reduce itching in older surgical patients
Treatments studied
Part of Skin clinical trials.
This trial tests whether a medication called esketamine, given during knee replacement surgery, can help reduce chronic itching in older adults. Chronic itching affects many seniors and can significantly impact quality of life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 65 years or older
- You have had itching on your skin (without obvious rashes) for more than 6 weeks, occurring daily or nearly daily
- You are scheduled for knee replacement surgery under general anesthesia
- Your weight and overall health allow safe surgery (BMI 18–30, no severe heart, lung, or liver problems)
- You have not taken opioid pain medications in the 48 hours before surgery
- You are not currently enrolled in another drug trial
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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