Esketamine and memory after oral surgery in older adults
Treatments studied
Part of Brain & nervous system, Mouth & dental clinical trials.
This trial tests whether a low-dose anesthetic called esketamine can help protect memory and thinking after oral or facial surgery in people aged 60 and older. If you are having this type of surgery and are worried about mental clarity afterward, this study may show if this medication helps.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 60 years or older.
- You are scheduled for oral, jaw, or face surgery under general anesthesia that will last at least 2 hours.
- You are in generally stable health (classified as ASA I–III).
- You do not have a history of mental health conditions or take antipsychotic medication.
- You do not have severe heart, lung, liver, or kidney disease.
- You have not been diagnosed with memory or thinking problems, and you can complete thinking tests.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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