Esketamine during surgery for itching from bile flow problems
Treatments studied
Part of Digestive system, Pain clinical trials.
This study tests whether giving a medicine called esketamine during your surgery helps reduce severe itching that comes from liver or bile duct problems. If you are already scheduled for this type of surgery, the medicine may give you extra relief from itching after the operation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have itching caused by a bile flow problem (like gallstones or bile duct blockage) and the itching is moderate to severe (score 4 or higher on a 0–10 scale).
- You are planning to have surgery on your liver, gallbladder, or bile ducts.
- You are 18 years or older and your weight is in a healthy range for your height (BMI between 18 and 30).
- You are generally healthy enough for surgery (classified as ASA I–III).
- You do not have other skin conditions, serious heart or lung problems, or severe liver failure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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