Clin2
NCT07598760Possibly a fitNot yet recruiting

Nerve Stimulation Therapy for Heart Failure With Strong Pumping

Hypertension (HTN)Heart Failure With Preserved Ejection Fraction (HFpEFHypertension, Systolic

Part of Heart & circulation clinical trials.

This trial tests a special pacemaker that uses nerve stimulation to help people with heart failure where the heart pumps normally but doesn't relax well. You would receive this device during a standard pacemaker procedure, and researchers would track how it affects your symptoms and quality of life.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
20 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older and need a dual-chamber pacemaker (a device that helps regulate heartbeat) or need to replace an existing one
  • You have been diagnosed with heart failure with preserved ejection fraction (HFpEF)—meaning your heart pumps at normal strength but doesn't fill or relax properly
  • You have a history of high blood pressure
  • Your heart failure symptoms are mild to moderate (NYHA class II or III: you feel short of breath with activity or have some limitations)
  • You are taking stable heart failure medications as prescribed by your doctor
  • You can sign a consent form showing you understand the study and agree to participate

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06678841Recruiting
Pacing therapy for heart failure with preserved pumping ability

This study tests a new pacing approach for people with a specific type of heart failure (HFpEF) to see if it can improve symptoms and quality of life. It involves a pacemaker-like device that adjusts heart rate based on your needs.

Phoenix, Arizona
NCT07560436Recruiting· Phase 2
Stents for Heart Failure With Normal Pumping

This trial tests whether placing stents in coronary arteries helps patients with heart failure who still have a strong-pumping heart. The study aims to see if improving blood flow to the heart reduces symptoms and improves quality of life.

London
NCT05441839Recruiting
Heart failure with preserved pumping function study in the UK

This trial studies people who have heart failure symptoms but whose heart pumping strength is largely preserved. It aims to better understand this specific type of heart failure and how best to treat or evaluate it.

Abercynon
NCT06560762Recruiting· Phase 1
Study of a new drug for heart failure with preserved pumping ability

This trial tests an investigational drug for people with a type of heart failure where the heart pumps normally but is stiff. The goal is to see if the drug can improve symptoms and quality of life.

Chicago, Illinois
NCT06992089Recruiting
Pacemaker study for heart failure with low heart rate

This trial tests a special pacemaker setting to help your heart beat faster during exercise. It may improve your ability to be active if you have heart failure with preserved ejection fraction (HFpEF) and a low resting heart rate.

Valencia
NCT03215849Enrolling by invitation
Tested pacing device for heart failure with preserved pumping

This trial studies a heart pacing approach in people with heart failure symptoms despite preserved heart pumping. It aims to see whether changing heart timing can improve how you feel and how your heart works during exercise.

Cardiff

Hear when a new Hypertension (HTN) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.