Testing Opioid-Free Surgery to Prevent Post-Surgery Confusion
Part of Brain & nervous system, Cancer, Digestive system, Mental health clinical trials.
This study tests whether avoiding opioid painkillers during surgery can reduce confusion and delirium that sometimes occurs after surgery in older adults. You'll receive anesthesia without opioids and be closely monitored before and after your planned digestive system surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 65 or older
- Scheduled for planned (non-emergency) stomach or bowel surgery
- Good enough overall health for surgery (ASA grade I–III, meaning no serious uncontrolled diseases)
- Weight in a healthy range (BMI 18–30)
- Some signs of age-related physical frailty (measured by a standard score)
- Normal thinking and memory before surgery (scored on a brief phone cognitive test)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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